What's new in angiogenesis?
► VEGF-D promotes tumor
metastasis - role of prostaglandins -
Kamezis et al.
Cancer Cell 2012
► Rapid decrease in chemotherapy
delivery by anti-VEGF therapy -
Van der Veldt et al.
Cancer Cell 2012
► PDGF-B boosts tumor growth by EPO
expression from stromal components -
Xue et al. Nature Medicine 2012
► Micro-RNA regulation of angiogenesis and
metastasis - Png et al. Nature
► Cancer stem cells reside in perivascular niche and get stimulated by
VEGF through neuropilin-1 - Beck et al.
Nature.
►
Tumor hypoxia promotes recruitment of Tregs through CC-chemokine ligand
28 (CCL28) - Facciabene et al. Nature.
► Acetylation dependent fine tuning of endothelial Notch signaling -
Guarani et al. Nature.
► Action mechanism of angiosuppression by Robo4
- Koch et al. Dev Cell.
► Macrophage polarization
and vessel normalization regulated by HRG -
Rolny et al. Cancer Cell
► Tumor blood vessels without
endothelium. Ricci-Vitiani et al,
Nature; Wang et al, Nature;
El Hallani et al, Brain.
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